안구건조증 환자에서 실리콘 눈물점 마개 삽입 전후의 눈물막 및 안구표면 변화

• 영문명: Changes of Ocular Surface after Silicone Punctal Plug Insertion in Patients with Dry Eye Syndrome
• 발행기관: 대한안과학회
• 저자명: 오한진 윤경철 박영걸,Han-Jin Oh, M.D., Kyung-Chul Yoon, M.D., Yeoung-Geol Park, M.D.
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume46,number11, 1774~1779쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2005.11.30

영문 초록

Purpose: To evaluate the changes in tear film and the ocular surface before and after punctal occlusion by silicone punctal plug insertion in dry eye patients. Methods: Twenty-four eyes of 19 patients with dry eye were included. We performed corneal sensitivity test, tear film break-up time (BUT), basal tear secretion test (BST), fluorescein staining, tear clearance test (Tcr), and conjunctival impression cytology and then compared the measurements before and after punctal occlusion. Results: Before silicone pucntal plug insertion corneal sensitivity, BUT, BST, fluorescein staining score, and Tcr were: 52.50±6.55 mm, 4.47±1.33 sec, 4.07±1.86 mm, 4.74±3.21 and 3.83±1.62, respectively. The grade of conjunctival squamous metaplasia was 2.45±1.26, and goblet cell density was 131.82±125.53 cells/mm2 before punctal occlusion. After punctal plug insertion corneal sensitivity was 58.13±3.72 mm (p=0.015), BUT was 6.76±2.59 sec (p<0.01), BST was 5.57±3.32 mm (p=0.161), fluorescein staining score was 1.74±2.13 (p<0.01) and Tcr was 4.50±1.29 (p=0.198). The degree of conjunctival squamous metaplasia was 1.12±0.83 (p=0.019) and goblet cell density was 206.67±155.78 cells/mm2 (p=0.229) after punctal plug insertion. Conclusions: The tear films and ocular surface changes after punctal plug insertion in dry eye patients include increased corneal sensitivity, improved quality of tear films and decreased conjunctival squamous metaplasia.

키워드

Ocular surface, Silicone punctal plug, Tear film