향유 지상부의 정유의 수종 항생제 내성 병원성 균주에 대한 억제효과

• 영문명: Study on Activities of the Essential Oil from Elsholtzia ciliata against Some Antibiotic-Susceptible and -Resistant Strains of Pathogenic Bacteria
• 발행기관: 대한약학회
• 저자명: 신승원(Seungwon Shin)
• 간행물 정보: 『약학회지』제54권 제2호 (2010년), 122~125쪽, 전체 4쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2010.04.30

영문 초록

The essential oil fraction was extracted from the aerial parts of the plant by steam distillation method and its composition was analyzed by GC-MS (gas chromatography-mass spectrometry) which led to the identification of 43 compounds. Dehydroelsholtzia ketone (56.81%) and elsholtzia ketone (30.05%) were identified as the predominant components of this oil. The antibacterial activities of the essential oil fraction were assessed by micro-dilution tests against antibioticsusceptible and -resistant strains of Streptococcus pneumoniae, Staphylococcus aureus, Salmonella enteritidis, and S. typhimurium. The oil inhibited most of the tested strains significantly resulting MICs (minimum inhibiting concentrations) between 2 mg/ml and >16 mg/ml. In most cases of this study Streptococcus pneumoniae and Staphylococcus aureus showed higher sensitivity to this oil than Salmonella strains.

키워드

essential oil Elsholtzia ciliata antibiotic-resistance elsholtzia ketone dehydroelsholtzia ketone Streptococcus pneumoniae Staphylococcus aureus Salmonella enteritidis S. typhimurium