물오리나무에서 분리된 Diarylheptanoid의 항산화작용

• 영문명: Antioxidative Effects of Diarylheptanoids from Alnus hirsuta
• 발행기관: 대한약학회
• 저자명: 이연아(Yeon Ah Lee) 조수민(Soo MIn Cho) 김광호(Kwang Ho Kim) 김준식(Jun Sik Kim) 김세원(Sae Won Kim) 이민원(Min Won Lee)
• 간행물 정보: 『약학회지』제44권 제2호 (2000년), 193~196쪽, 전체 4쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2000.04.29

영문 초록

Four diarylheptanoids oregonin, hirsutanonol, 1,7-bis-(3,4-dihydroxyphenyl)-heptane-5-0-beta-D-xylopyranoside and 1,7-bis-(3,4-dihydroxyphenyl)-heptane-5-0-beta-D-glucopyranoside isolated from Alnus hirsuta were evaluated for their antioxidative effects with 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical and lipid peroxidation generation system mediated by addition of H202 and/or Fe2+, to rat liver homogenate. All these diarylheptanoids showed significant inhibitory activities against the DPPH radical and demonstrated strong activities in preventing the lipid peroxidation induced by H202.

키워드

Alnus hirsuta Antioxidative effect DPPH Lipid peroxidation inhibition Diarylheptanoid.