참당귀지상부의 플라보노이드 성분 및 생리활성

• 영문명: Flavonoid Compounds and Biological Activities on the Aaerial Parts of Angelica gigas
• 발행기관: 대한약학회
• 저자명: 문형인(Hyung In Moon) 안규태(Kyu Tai Ahn) 이강노(Kang Ro Lee) 지옥표(Ok Pyo Zee)
• 간행물 정보: 『약학회지』제44권 제2호 (2000년), 119~127쪽, 전체 9쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2000.04.29

영문 초록

This paper describes isolation and elucidation structure of the components from leaves and evaluate the radical scavenging activity on DPPH radical for antioxidant effect. Bioassay guided fractionation of MeOH extract afforded active EtOAc and BuOH fractions. The most active EtOAc fraction was repeatedly chromatographed over silica and Sephadex LH-20 to afford six flavonoid compounds. Studies on the antioxidant activity of these constituents showed that quercetin was the most active of these compounds. Luteolin and kaempherol are also active, These results suggested that the antioxidant activity of leaves of Angelica gigas may be due to flavonoid components. All the compounds were identified by spectroscopic methods and are the first report from leaves of Angelica gigas.

키워드

Angelica gigas Nakai leaves：flavonoid antioxidant effect.