슬관절치환술 환자의 Cephalosporin계 항생제 사용에 대한 경제효율성 비교연구

• 영문명: A Comparative Study of Use of Cephalosporins in Total Knee Replacement Surgery in Terms of Economic Efficiency
• 발행기관: 대한약학회
• 저자명: 조동선(Dong Sun Cho) 송현주(Hyun Ju Song) 박성욱(Sung Uk Park) 손의동(Uy Dong Sohn)
• 간행물 정보: 『약학회지』제52권 제2호 (2008년), 101~110쪽, 전체 10쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2008.04.30

영문 초록

Total Knee Replacement (TKR) surgery is one of the invasive procedures for patients with late-stage knee joint disorders. In the present study, economic efficiency was compared between uses of the 2nd and 3rd generation cephalosporins for the prophylaxis before and after the surgery using frequency analysis in terms of various factors such as medication costs, the number of days of antibiotic use and hospitalization due to TKR surgery. The results showed that the 3rd generation cephalosporins did not reduce the infection rate and total medication costs, but rather raised antibiotic cost in comparison with the 2nd ones. A frequent use of the 3rd ones is closely related to emergence or resistant bacterial strains. Therefore, we suggest that unnecessary prescriptions for the broad spectrum antibiotics should be avoided.

키워드

antibiotics cephalosporin economic efficiency TKR