유산균에 의한 장내미생물효소의 저해

• 영문명: Inhibition of Intestinal Bacterial Enzymes by Lactic Acid Bacteria
• 발행기관: 대한약학회
• 저자명: 김동현(Dong Hyun Kim) 한명주(Myung Joo Han)
• 간행물 정보: 『약학회지』제39권 제2호 (1995년), 169~174쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1995.04.28

영문 초록

By coculturing E. coli HGU-3 with Bifidobacterium KH-2 or Streptococcus faecalis HGO-7 with Bifidobacterium KH-2, the productivity of beta-glucuronidase and beta-glucosidase was inhibited. When lactulose, growth factor of lactic acid bacteria, was added into this medium, the productivity of these enzymes and pH of the medium were dramatically decreased. When intestinal microflora of human and rat were inoculated in the medium containing lactulose, the enzyme productivity and pH of the medium were dramatically decreased. By s.c. injecting DMH into mice, beta-glucuronidase of intestinal bacteria was induced, but the production of the enzymes was inhibited by adminstering lactulose.