인삼 Butanol Fraction이 Streptozotocin 유발 고혈당 쥐에 미치는 작용에 관한 연구

• 영문명: Effect of Ginseng Butanol Fraction on the Streptozotocin-induced Hyperglycemic Rats
• 발행기관: 대한약학회
• 저자명: 허인회(In Hoi Huh) 김대영(Dai Young Kim)
• 간행물 정보: 『약학회지』제27권 제3호 (1983년), 215~220쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1983.09.30

영문 초록

To elucidate the effect of ginseng butanol fraction on streptozotocin-induced hyperglycemia, ginseng butanol fraction was administered before and after injection of streptozotocin(50mg/kg, i.v.), and glucose, insulin, and cholesterol levels in serum were determined at 96 hours after streptozotocin injection. Serum glucose, insulin levels were significantly decreased by administration of ginseng butanol fraction (100mg/kg, p.o.) at 7 hour and 7, 4, 1, hour(three times) before streptozotocin injection. The glucose levels were significantly decresed by administration of ginseng butanol fraction at 1 hour(100mg/kg) after streptozotocin injection, and also serum glucose levels in groups of continuous administration of ginseng butanol fraction(100mg/kg) for 3 days after streptozotocin injection were markedly decreased than in group of single dose of ginseng butanol fraction. Ginseng butanol fraction has the protective and relieving action against streptozotocin-induced hyperglycemia.