3년간 치료를 지속한 정신과 외래 노인 환자에서의 다제요법에 대한 연구

• 영문명: A Study on Polypharmacy in the Elderly Psychiatric Outpatients with Persistent Treatments for 3 years
• 발행기관: 대한노인정신의학회
• 저자명: 유해선(Hae-Sun Yoo) 정인과(In-Kwa Jung)
• 간행물 정보: 『노인정신의학』노인정신의학 제14권 제1호, 50~57쪽, 전체 8쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2010.06.30

영문 초록

Objectives : The objective of this study was to investigate the prescription trends for the elderly psychiatric outpatients at a university hospital. Methods : We performed a retrospective study based on medical records. Data on 146 elderly patients (65 years and older) diagnosed with psychiatric disorders according to ICD-10 from January 2005 to March 2008 were collected. Analyses were performed regarding demographic characteristics, prevalence of polypharmacy, and the doses and types of drugs prescribed. Results : In 146 subjects, the mean age was 76.14±5.21. More than five types of drugs were prescribed to 49.5% of the patients in 2008. The percentage of stable users (those without changes in the category of polypharmacy for 3 years) was 69.8%. Each patient received an average of 4.20±1.50 kinds of drugs in 2005 and 4.02±1.77 in 2008. The average dose of drugs was 6.1±3.50 in 2005 and 6.49±4.09 in 2008, and the difference was not statistically significant. The average number of types of psychiatric drugs prescribed to the patients decreased from 2.37±0.86 in 2005 to 2.17±0.87 in 2008 (p<0.05). Conclusion : Although practice of polypharmacy showed a slow increase over the 3 years from 2005 to 2008, almost half of the elderly patients we studied received multiple drugs. Since polypharmacy can increase drug-drug interactions and adverse effects in the elderly, appropriate drug monitoring and careful prescription are necessary.

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노인 다제요법 정신과적 약물 The elderly Polypharmacy Psychiatric drugs