사지 악성 육종에서 보존적 수술후 방사선 치료의 역할

• 영문명: The Role of Conservative Surgery and Radiation Therapy for the Extremity Soft Tissue Sarcomas
• 발행기관: 대한방사선종양학회
• 저자명: 김우철(Woo Cheol Kim) 서창옥(Chang Ok Suh) 김귀언(Gwi Eon Kim) 박광화(Kwang Hwa Park) 신동환(Dong-Hwan Shin) 이경희(Kyung Hee Lee)
• 간행물 정보: 『대한방사선종양학회지』제11권 제2호, 411~419쪽, 전체 9쪽
• 주제분류: 의약학 > 종양학
• 파일형태: PDF
• 발행일자: 1993.12.29

영문 초록

A total of 44 patients with extremity soft tissue sarcomas had received conservative surgery and radiation therapy in the Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University College of Medicine between Jan. 1980 and Dec. 1990. Initial surgical treatment consisted of intracapsular excision in 33 patients (75%), marginal excision in 9 patients, and wide excision in two patients. Total radiation doses were between 40Gy and 65Gy (median 60 Gy). Median follow-up period was 47 months. Overall actuarial 5-year survival rate was 76.9% and 5-year recurrence free survival rate was 39.3%. There was no statistically significant prognostic factors but the 5-year survival rates tended to be decreased in the patients with high grade tumors and treated with narrow surgical extent. Sixteen patients recurred during fellow-up (16/31, 51.6%). The incidence of initial local recurrence was 22.6% (7/31) and distant metastasis was 29%(9/31). Of the 7 who did not have metastasis at diagnosis of local recurrence, 5 were submitted to a salvage treatment. All of them achieved local control and distant metastasis appeared in three of them. In conclusion, conservative surgery and radiation therapy in the patients with extremity soft tissue sarcomas was the effective treatment modality.

키워드

Extremity Soft Tissue Sarcoma Conservative Surgery Radiotherapy