중고도비만 환자에 대한 가미태음조위탕의 활용: 후향적 차트 리뷰

• 영문명: Gamitaeeumjowee-tang for Patients with Class Ⅱ or Ⅲ Obesity: A Retrospective Chart Review
• 발행기관: 한방비만학회
• 저자명: 이유빈 이아름 손민주 안시현 한지연
• 간행물 정보: 『대한한방비만학회지』제24권 제1호, 54~67쪽, 전체 14쪽
• 주제분류: 의약학 > 한의학
• 파일형태: PDF
• 발행일자: 2024.06.30

국문 초록

Objectives: The purpose of this study was to evaluate changes in body weight and blood pressure and also analyze adverse events after weight loss program using Gamitaeeumjowee-tang in patients with class Ⅱ or Ⅲ obesity, considering for metabolic and bariatric surgery. Methods: A retrospective chart review was conducted on class Ⅲ obesity or class Ⅱ obesity patients with comorbidities, who participated in 24-week weight loss program using Gamitaeeumjowee-tang (n=54). The analysis included changes in body weight, body mass index, fat mass, skeletal muscle mass, waist-hip ratio and blood pressure before and after the program. And also calculated the proportion of patients who lost more than 5%, 10%, and 15% of their initial weight. Adverse events were assessed by causality, severity and system-organ classes. Results: After the weight loss program, body weight decreased 12.21±6.43 kg (12.77%), and BMI decreased 4.61±2.25 kg/m2 (12.75%) on average (P<0.05). The 90.7% of the subjects lost more than 5% of their weight, 68.5% lost more than 10%, and 35.1% lost more than 15% of their weight. Blood pressure significantly decreased 11.04±14.53 mmHg in systolic and 7.28±11.89 mmHg in diastolic on average (P<0.05). The 97% of adverse events were mild, and 75% were evaluated as ‘unlikely’ in the causality evaluation. Conclusions: The results of this study, the weight loss program using Gamitaeeumjoweetang showed significant weight loss and blood pressure reduction in patients with class Ⅲ obesity or class Ⅱ obesity with comorbidities, without serious adverse events. Well-designed clinical studies are recommended for the future.

목차

서론

대상 및 방법

고찰

결론

References

키워드

Herbal medicine Obesity Weight loss Blood pressure