문헌 분석을 통한 소아청소년 세신 처방의 안전성 고찰

• 영문명: A Study on the Safety of Asarum Sieboldii, Asarum Heterotropoides for Pediatrics through Literature Analysis: Focusing on Aristolochic Acid
• 발행기관: 대한모유수유한의학회
• 저자명: 김병찬(Byung Chan Kim) 김태환(Tae Hwan Kim)
• 간행물 정보: 『모자보건과 기능영양』제4권 제1호, 1~12쪽, 전체 12쪽
• 주제분류: 의약학 > 한의학
• 파일형태: PDF
• 발행일자: 2023.12.31

영문 초록

Objectives: This study was conducted to review safety of herbal medicine for pediatrics, especially Asarum sieboldii, Asarum heterotropoides, and to design herbal medicine safety assessment model. Methods: Literature search was done to study safety of herbal medicine for pediatrics, especially Asarum sieboldii, Asarum heterotropoides. UptoDate, Pubmed, Google Scholarship, DBPIA were used in the research. Search words were ‘pediatrics AND herbal medicine’, ‘Safety of Herbal treatment’, ‘Asarum sieboldii’, ‘Asarum heterotropoides’, etc. Results: 5 steps of herbal medicine safety assessment model were planned and done. Those include chemical structure analysis, pathologic analysis, pharmokinetics analysis, dosage - toxicology analysis, bibliographic analysis. Through the 5 assessment steps, we estimated that aristolochic acid nephropathy’s risk factor can be infants below 36 months, renal failure. We also estimated the safety standard for the herbal medicine and the calculation were same by dosage-toxicology and bibliographic analysis. We also found out that while reading medical book from past, the doctor should pay attention to drug taking methods. Conclusions: 5 steps of herbal medicine safety assessment model should be introduced to other herbal medicines for fast assessment by the doctors before prescripting to pediatrics. However, backup experimental data, safety clinical trials for pediatrics should be more held for further evidence.

목차

Ⅰ. 서 론

Ⅱ. 방 법

Ⅲ. 결 과

Ⅳ. 고 찰

Ⅴ. 결 론

참고문헌

키워드

Safety Herbal Medicine Pediatrics Aristolochic acid Asarum Sieboldii Asarum Heterotropoides