학술논문
Evaluation of Asymmetric Dimethylarginine, Malondialdehyde, and Vitamin Levels of Borderline Personality Disorder Patients With and Without Self-Mutilation
이용수 3
- 영문명
- 발행기관
- 대한신경정신의학회
- 저자명
- Selda Telo Sema Baykara
- 간행물 정보
- 『Psychiatry Investigation』제20권 제12호, 1142~1147쪽, 전체 6쪽
- 주제분류
- 의약학 > 정신과학
- 파일형태
- 발행일자
- 2023.12.31
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국문 초록
Objective Believing that oxidative stress may be increased in borderline personality disorder (BPD) patients with self-mutilating behav-iors (SMB), we aimed to measure serum asymmetric dimethylarginine (ADMA) and malondialdehyde (MDA) levels in these patients.
Methods The study included 60 patients diagnosed with BPD and 30 healthy controls. BPD patients were divided into two groups: 30 female patients with SMB and 30 female patients with no-self-mutilating behavior (NSMB). ADMA, MDA, vitamin A, and vitamin E lev-els were analyzed. Beck Anxiety Inventory (BAI) and Beck Depression Inventory (BDI) were conducted with the participants.
Results Serum ADMA and MDA levels were higher in SMB and NSMB group compared to control group. Serum vitamin E levels were also lower in the SMB group compared to the control group. Positive correlations were determined between both ADMA and MDA, and between BDI and BAI scores. Also, BAI scores were statistically higher in SMB group compared to NSMB group.
Conclusion It was discovered that levels of ADMA and MDA, which reflected oxidative stress, were elevated in patients with BPD who exhibited SMB. Accordingly, future studies should investigate the role of oxidative stress in a more comprehensive way in terms of the dif-ferent mechanisms underlying and treatments involved in borderline personality disorder.
영문 초록
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
키워드
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