Association between obesity and high-sensitivity C-reactive protein in Korean adults without cardiovascular disease

• 영문명: Association between obesity and high-sensitivity C-reactive protein in Korean adults without cardiovascular disease
• 발행기관: 한국기초간호학회
• 저자명: 이혜순
• 간행물 정보: 『Journal of Korean Biological Nursing Science』제25권 제1호, 32~42쪽, 전체 11쪽
• 주제분류: 의약학 > 의학일반
• 파일형태: PDF
• 발행일자: 2023.02.28

영문 초록

Purpose: This study aimed to investigate the association between obesity and high-sensitivity C-reactiveprotein (hs-CRP) levels in Korean adults without cardiovascular disease (CVD). Methods: The subjects were 3,634 adults, and data were extracted from the seventh Korea NationalHealth and Nutrition Examination Survey (KNHANES Ⅶ-3). A complex sampling design analysis wasapplied to reflect the stratified and clustered weights. The data were analyzed using the complex sampleRao-Scott chi-square test and multiple logistic regression analysis (in SPSS for Windows version26.0). Obesity, according to body mass index (BMI), was defined as obesity (BMI = 25-29.9 kg/m2),high obesity (BMI = 30-34.9 kg/m2), and super-high obesity (BMI ≥ 35 kg/m2), and abdominal obesity(AO) was defined as a waist circumference (WC) ≥ 90 cm in males and WC ≥ 85 cm in females. Results: The odds ratios for moderate CVD risk (hs-CRP; 1-3 mg/dL) were 2.21, 4.16, and 7.13 in theobesity, high obesity, and super-high obesity groups, respectively, compared to the normal BMI group. The odds ratio for moderate CVD risk was 2.18 in males with AO and 1.88 in females with AO. The oddsratios for high CVD risk (hs-CRP > 3 mg/L) were 4.40 and 17.55 in the high obesity and super-highobesity groups, respectively, compared to the normal BMI group. Conclusion: This study provides evidence that early detection and prevention programs for CVD shouldinclude obesity-related interventions aiming to modulate hs-CRP.

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INTRODUCTION

METHODS

RESULTS

DISCUSSION

CONCLUSION

키워드

Obesity Waist Circumference C-Reactive Protein Cardiovascular Diseases