공황 발작으로 인한 응급실 내원과 대기 오염의 연관성

• 영문명: Emergency Department Visits for Panic Attacks and Ambient Air Pollution: A Time-Stratified Case-Crossover Analysis
• 발행기관: 대한신경정신의학회
• 저자명: 문영경(Young Kyung Moon) 이원윤(Wonyun Lee) 오세현(Sehhyun Oh) 김호(Ho Kim) 명우재(Woojae Myung) 이혜원(Hyewon Lee) 김
• 간행물 정보: 『신경정신의학』제60권 제3호, 213~222쪽, 전체 10쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2021.08.31

영문 초록

Objectives This study investigates the association between short-term exposure to air pollutants and panic attacks requiring emergency department (ED) visits. Methods We identified 1926 patients who visited EDs in Seoul with panic attacks as the primary cause during the period from 2008 to 2014. We estimated short-term exposure to particles <2.5 μm (PM2.5), particles <10 μm (PM10), nitrogen dioxide (NO₂), sulfur dioxide (SO₂), ozone (O₃), and carbon monoxide (CO). We applied a time-stratified case-crossover study design and conducted a conditional logistic regression analysis to assess the association between air pollutants levels and ED visits due to panic attacks. Results Increasing O₃ concentration was significantly associated with an increased risk of panic attacks requiring ED visits (odds ratio: 1.15; 95% confidence interval: 1.04-1.27) on the same day of exposure. This association was robust to the sensitivity analysis using two pollutant models. Conclusion Our results show that short-term exposure to elevated O₃ concentration is associated with the exacerbation of panic attacks. This finding strongly suggests the detrimental effects of O₃ on major public health problems and provides insights for further research to investigate the causal associations between air pollution and poor mental health.

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대기 오염 오존 공황 발작 공황 장애 환자-교차 연구 Air pollutants Ozone Panic attack Panic disorder Case-crossover design