Effect of bleeding on the surgical field in dexmedetomidine infusion patients undergoing endoscopic sinus surgery under general anesthesia

• 발행기관: 조선대학교 의학연구원
• 저자명: Kwangrae Cho Inwook Myoung
• 간행물 정보: 『The Medical Journal of Chosun University』제45권 제2호, 62~69쪽, 전체 8쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2020.10.31

영문 초록

Background: In order to secure an ideal surgical field for endoscopic sinus surgery (ESS), it is necessary to reduce intraoperative bleeding. Intraoperative intra-nasal bleeding is influenced by various anesthetics. The present study focuses on the differences between sevoflurane/ remifentanil (SR)-based anesthesia and sevoflurane/remifentanil/dexmedetomidine (SRD)- based anesthesia in terms of surgical field conditions. Methods: American Society of Anesthesiologists physical status class I or II patients undergoing ESS were randomly assigned to the SR (n=36) or SRD (n=32) group. In order to assess the visibility of the surgical field, the level of intraoperative bleeding was rated on a 6-point numeric rating scale (NRS). Computed tomography findings were used to evaluate the extent of each preoperative surgical lesion, as high (＞12) vs. low (≤12) Lund-Mackay (LM) score. A single surgeon was in charge of rating the visibility of the surgical field on an NRS every 5 minutes, and the worst NRS was used as a representative value for each group. Results: The NRS of the surgical field was not significantly different between the two groups (p=0.089). However, in the high-LM score patients, the NRS of the surgical field was significantly better in the SRD group than in the SR group (p=0.009). Conclusions: In the high- LM score patients, SRD-based anesthesia resulted in better surgical field conditions for ESS than did SR-based anesthesia. Therefore, we conclude that SRD-based anesthesia is beneficial in ESS.

목차

INTRODUCTION

MATERIALS AND METHODS

RESULTS

DISCUSSION

REFERENCES

키워드

Dexmedetomidine Remifentanil Sinusitis