두경부 편평세포암종에서 c-erbB 수용체, MMP 및 VEGF 발현

• 영문명: Expression of c-erbB receptors, MMPs and VEGF in head and neck squamous cell carcinoma
• 발행기관: 조선대학교 의학연구원
• 저자명: 임성철(Sung-Chul Lim)
• 간행물 정보: 『The Medical Journal of Chosun University』제30권 제3호, 1~6쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2005.12.31

영문 초록

Head and neck squamous cell carcinomas (HNSCC) are characterized by a marked propensity for local invasion and cervical lymph node metastasis. The aim of this article was to review the expression of epidermal growth factor receptor (EGFR), c-erbB-2, vascular endothelial growth factor (VEGF) and matrix metalloproteinases (MMPs) in HNSCC patients and to study their possible correlation to various clinicopath이ᄋgic parameters. Based on this review, the expression of EGFR, c-erbB-2, VEGF, or MMPs play important roles for tumor growth, invasion and metastasis in HNSCC. c-erbB receptors, MMPs and VEGF might aid the clinician in the selection of an appropriate therapy for individual patients and help to predict the prognosis of patients.

키워드

EGFR c-erbB-2 VEGF MMP Squamous cell carcinoma