제 2형 당뇨병 환자에서 대사증후군의 유병률 및 관련요인의 특징

• 영문명: The Prevalence and The Characteristics of Related Factor in Metabolic Syndrome with Type 2 Diabetic Patients
• 발행기관: 조선대학교 의학연구원
• 저자명: 박철진(Chol-Jin Park) 박거운(Keo-Woon Park) 박일구(Il-Goo Park) 신지혜(Ji-Hae Shin) 김진화(Jin-Hwa Kim) 배학연(Hak-Yeo
• 간행물 정보: 『The Medical Journal of Chosun University』제32권 제3호, 71~78쪽, 전체 8쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2007.10.31

영문 초록

Background: People with insulin resistance has a higher risk of developing cardiovascular disease. This leads to the importance in diagnosing metabolic syndrome. The incidence of metabolic syndrome has increased significantly in korea because of an increased population of obese people and also the incidence of DM. There have been many studies done on the incidence of metabolic syndrome in the general population. Therefore, the authors have designed this study to identify the incidence of metabolic syndrome in patients with type 2 DM and also the associated characteristics in that population. Methods: The study included 169 adults over the age o f 20 (84 males and 85 females) admitted to the endocrinology department of Chosun University between Jan, 1st 2005 and May, 31st 2006. Out of the people diagnosed with type 2 DM people were excluded when any of the physical measurements (height, weight, blood pressure, abdominal circumference) and blood measurements (TG, HDL-cholesterol, fasting blood sugar) were insufficient and when the patient was taking any drugs other than anti-hypertensive agents and oral anti-diabetic agents. Obesity and the other risk factors were defined by the Asian-Pacific guideline and 2001 ATP III of NCEP, respectively. Result: The each prevalence according to the metabolic syndrome criteria of the type 2 DM patients showed low HDL cholesterolemia with the highest incidence of 57.4% followed by hypertriglyceridemia(52.0%), obesity(40.9%) and hypertension(33.0%). The each incidence of diagnostic criteria in metabolic syndrome according to sex was different. In males, hypertriglyceridemia was the highest with the incidence of 57.7% followed by low HDL-cholesterolemia(49.5%), obesity(40.0%) and hypertension (30.0%). In women, the incidence were low HDL-cholesterolemia(64.8%), hypertriglyceridemia(47.6%), obesity(45.0%) and hypertension(36.0 %), in a descending order. The analysis between the diagnosis of metabolic syndrome in type 2 DM patients and the criteria showed that hypertriglyceridemia (correlative value 0.575) had the highest correlation followed by low HDL-cholesterolemia (correlative value 0.446)，obesity (correlative value 0.350) and hypertension (correlative value 0.410). All the correlations were statistically significant with a p-value less than 0,01. Conclusions: Type 2 DM is a important factor of metabolic syndrome based on insulin resistance. The control of blood glucose with prevention and early diagnosis of the other factors related to metabolic syndrome in type 2 DM is important for preventing cardiovascular complications.

목차

서 론

대상 및 방법

결 과

고찰 및 결론

키워드

metabolic syndrome obesity type 2 DM