급성 허혈성 뇌졸중과 수면호흡장애의 관련성에 대한 연구

• 영문명: Study of Interaction between Sleep-disordered Breathing and Acute Ischemic Stroke
• 발행기관: 조선대학교 의학연구원
• 저자명: 이현진(Hyun Jin Lee) 허욱(Wook Hur) 정지연(Ji Yeon Jeong) 추인성(In Sung Choo) 김동욱(Dong Uk Kim) 안성환(Seong Hwan
• 간행물 정보: 『The Medical Journal of Chosun University』제37권 제4호, 256~261쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2012.12.31

영문 초록

Sleep-disordered breathing (SDB) is suggested to have a strong association with ischemic strokes. Risk factors, stroke subtypes, stroke lesion distribution, and the outcome of SDB in stroke patients are not fully studied in Korea. We prospectively studied 293 patients with acute ischemic stroke. Cardiovascular risk factors, stroke severity, sleep-related stroke onset, distribution of stroke lesions, and 3-month modified Rankin scores (mRS) were assessed. Stroke severity was assessed by National Institute of Health Stroke Scale (NIHSS) and mRS. The apnea-hypopnea index(AHI) was determined 6.3 土 2.2 days after stroke onset with a portable sleep apnea monitoring device. The incidence of SDB was 63.1%. The SDB group showed older age, higher NIHSS and mRS, more bulbar weakness, and higher incidence of sleep-related stroke onset. Among risk factors, alcohol consumption and atrial fibrillation were significantly associated with SDB of stroke patient. The SDB patients showed worse stroke outcome than those without SDB. Particular lesion location or specific stroke syndrome did not show any correlation. Higher NIHSS and bulbar involvement in SDB group seem to show the influence of ischemic stroke on the increased SDB incidence.

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키워드

Acute ischemic stroke Incidence Sleep disordered breathing