수면관련 호흡장애에서의 신경정신과적 증상

• 영문명: Neuropsychiatric Dysfunction in Sleep-Related Breathing Disorders
• 발행기관: 대한수면의학회
• 저자명: 윤인영
• 간행물 정보: 『수면정신생리』제4권 제2호, 140~146쪽, 전체 7쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 1997.12.31

영문 초록

Sleep-related breathing disorders, especially sleep apnea syndrome are complicated by neuropsychiatric dysfunction such as excessive daytime sleepiness, cognitive dysfunction, and depression. As the determinants of daytime sleepiness, sleep fragmentation is more influential than nocturnal hypoxia. Daytime sleepiness can be improved by continuous positive airway pressure (CPAP) or surgery in up to 95% of the treated subjects. Both sleepiness and nocturnal hypoxia would cause cognitive dysfunction. While impairments in attention and verbal memory are more related with sleepiness and prominent in mild to moderate sleep apnea syndrome (SAS), impairments in general intellectual function and executive function are more related with nocturnal hypoxia and prominent in severe SAS. Several cognitive deficits related with nocturnal hypoxia may be irreversible despite CPAP or surgical treatments. So, early detection and early appropriate treatment of SAS would prevent sleepiness and cognitive deterioration.

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키워드

수면무호흡증 주간졸림증 인지기능의 장애 수면분절 저산소증 sleep apnea syndrome daytime sleepiness cognitive dysfunction sleep fragmentation nocturnal hypoxia