뇌척수액 백혈구 증가증이 없는 장바이러스 뇌수막염 소아들의 임상적 특징

• 영문명: Clinical Manifestation of Enteroviral Meningitis without Cerebrospinal Fluid (CSF) Pleocytosis in Children
• 발행기관: 조선대학교 의학연구원
• 저자명: 조철준(Chul Jun Cho) 남명수(Myoung Soo Nam) 김용욱(Yong Wook Kim) 김경심(Kyoung Sim Kim) 조형민(Hyung Min Cho) 김 령(
• 간행물 정보: 『The Medical Journal of Chosun University』제43권 제2호, 88~93쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2018.10.31

영문 초록

The aim of this study was to investigate the factors associated with cerebrospinal fluid (CSF) pleocytosis in pediatric entero-viral meningitis. A retrospective analysis of the medical records was performed in 281 patients under 18 years of age who were diagnosed with enteroviral meningitis by reverse transcription-polymerase chain reaction (RT-PCR) at Kwangju Chris-tian Hospital from January to December 2016. Clinical symptoms and laboratory findings were compared according to the presence or absence of CSF pleocytosis. 112 children (39.9%) did not have CSF pleocytosis. When we compared the group of meningitis without pleocytosis and the group with pleocytosis, age were younger (< 2years), and the interval between onset of symptoms and the time of lumbar puncture was shorter (<24 hours), peripheral white blood cell counts were lower, but C-reactive protein (CRP) was higher in the group of meningitis without pleocytosis. Enteroviral meningitis should not be excluded even if CSF pleocytosis is not seen in patients. And enterovirus CSF RT-PCR should be performed with high sus-picion in children younger than 2 years.

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키워드

Cerebrospinal fluid Pediatrics Enterovirus Meningitis RT-PCR