Coexistence of Chronic Myelogenous Leukemia and Diffuse Large B-Cell Lymphoma

• 영문명: Coexistence of Chronic Myelogenous Leukemia and Diffuse Large B-Cell Lymphoma
• 발행기관: 조선대학교 의학연구원
• 저자명: Hee-Jeong Lee Choon-Hae Chung Chi-Young Park
• 간행물 정보: 『The Medical Journal of Chosun University』제40권 제4호, 178~180쪽, 전체 3쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2015.12.31

영문 초록

Diagnosis of chronic myelogenous leukemia (CML) and non-Hodgkins lymphoma (NHL) have rarely been made simultaneously in the same patient. We report a rare case of a patient with CML-chronic phase who developed a concurrent Philadelphia (Ph)-negative diffuse large B-cell lymphoma. At the time of diagnosis, cytogenetic analysis of peripheral blood and bone marrow cells revealed the Ph-chromosome translocation in all examined metaphases. A lymph node biopsy showed features of diffuse large B-cell lymphoma, and fluorescence in situ hybridization (FISH) of lymph node tissue for BCR-ABL was negative. The patient was treated with R-CHOP (rituximab, cyclophosphamide, vincristine, adriamycin and prednisone) and imatinib mesylate.

목차

Introduction

Case Description

Discussion

키워드

chronic myelogenous leukemia non-Hodgkins lymphoma