한국인에서 발생한 만성 B형 간염 환자에서 테노포비어의 단기 치료 효과

• 영문명: Treatment Efficacy of Tenofovir in Korean Patients with Chronic Hepatitis B after Twelve Months of Treatment
• 발행기관: 조선대학교 의학연구원
• 저자명: 주종석(Jong Seok Ju) 강성훈(Sung Hoon Kang) 김석원(Seok Won Kim) 신해진(Hae Jin Shin) 이엄석(Eaum Seok Lee) 김석현(Se
• 간행물 정보: 『The Medical Journal of Chosun University』제39권 제3호, 120~125쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2014.09.30

영문 초록

The aim of this study was to evaluate the efficacy of tenofovir in HBV patients at 12 months after treatment. A total of 122 chronic hepatitis B patients who took tenofovir for at least 12 months were enrolled. We measured ALT levels, HBeAg, anti-HBe, HBV DNA, and serum creatinine at six and 12 months after treatment. The virological response rate at six and 12 months after treatment in naïve patients was 27.1% and 41.7%, respectively. High virological response rate at six and 12 months after treatment showed an association with initial low HBV DNA titer and initial negative HBeAg status.

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키워드

Chronic Hepatitis B Tenofovir