급성기 양극성우울증 약물치료 전략

• 영문명: Pharmacological Treatment Strategies for Acute Bipolar Depression
• 발행기관: 대한신경정신의학회
• 저자명: 김세주(Se Joo Kim)
• 간행물 정보: 『신경정신의학』제57권 제4호, 287~300쪽, 전체 14쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2018.11.30

영문 초록

Of the different phases of bipolar disorder, bipolar depression is more prevailing and is more difficult to treat. However, there is a deficit in systemic research on the pharmacological treatment of acute bipolar depression. Therefore, consensuses on the pharmacological treatment strategies of acute bipolar depression has yet to be made. Currently, there are only three drugs approved by the Food and Drug Administration for acute bipolar depression : quetiapine, olanzapine-fluoxetine complex, and lurasidone. In clinical practice, other drugs such as mood stabilizers (lamotrigine, lithium, valproate) and/or the other atypical antipsychotics (aripiprazole, risperidone, ziprasidone) are frequently prescribed. There remains controversy on the use of antidepressants in bipolar depression. Here, we summarized the evidence of current pharmacological treatment options and reviewed treatment guidelines of acute bipolar depression from recently published studies.

키워드

Acute bipolar depression Treatment guideline Atypical antipsychotics Mood stabilizers Antidepressants 급성기 양극성우울증 치료 가이드라인 비정형항정신병약물 기분안정제 항우울제