Fluoride가 적출장기(摘出臟器)의 Catecholamine 유리(遊離) 및 Monoamine Oxidase 활성도(活性度)에 미치는 영향(影響)

• 영문명: The Influence of Sodium Fluoride on the Release of Catecholamine from Perfused Organs and Monoamine Oxidase Activity
• 발행기관: 대한약리학회
• 저자명: 천연숙(Cheon, Yun-Sook) 김성숙(Kim, Sung-Sook) 이경희(Lee, Kyung-Hee) 신경철(Shin, Kyung-Chul)
• 간행물 정보: 『대한약리학잡지』제8권 제2호, 41~48쪽, 전체 8쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1972.12.31

영문 초록

Fluorides were supposed to exert a stimulatory action on the catecholamine release. In this study, the authors attempted to investigate the action of sodium fluoride on the catecholamine release from the isolated perfused cow adrenal gland and rat heart. And also the inhibitory effect of sodium fluoride on the monoamine oxidase activity in rat heart and liver mitochondria was investigated. The monoamine oxidase activity was measured by the conversion of benzylamine to benzaldehyde. The results obtained were follows; 1. Sodium fluoride stimulated the release of catecholamine from the isolated perfused cow adrenal gland and rat heart. 2. Sodium fluoride inhibited the rat heart and liver mitochondrial monoamine oxidase activity.