MicroRNA-1 in Cardiac Diseases and Cancers

• 영문명: MicroRNA-1 in Cardiac Diseases and Cancers
• 발행기관: 대한생리학회-대한약리학회
• 저자명: Jianzhe Li Xiaomin Dong Zhongping Wang Jianhua Wu
• 간행물 정보: 『The Korean Journal of Physiology & Pharmacology』제18권 제5호, 359~363쪽, 전체 5쪽
• 주제분류: 의약학 > 의학일반
• 파일형태: PDF
• 발행일자: 2014.01.01

영문 초록

MicroRNAs (miRs) are endogenous ≈22-nt non-coding RNAs that participate in the regulation of gene expression at post-transcriptional level. MiR-1 is one of the muscle-specific miRs, aberrant expression of miR-1 plays important roles in many physiological and pathological processes. In this review, we focus on the recent studies about miR-1 in cardiac diseases and cancers. The findings indicate that miR-1 may be a novel, important biomarker, and a potential therapeutic target in cardiac diseases and cancers.

키워드

Cancers Cardiac diseases MicroRNA-1