학술논문
Decreased Expression of PTEN in Olfactory Bulb of Rat Pub after Naris Closure
이용수 0
- 영문명
- Decreased Expression of PTEN in Olfactory Bulb of Rat Pub after Naris Closure
- 발행기관
- 대한생리학회-대한약리학회
- 저자명
- Jaeyoung Cho Sang-Hyun Lee Geon Hee Lee Wanjoo Chun Yee-Tae Park,
- 간행물 정보
- 『The Korean Journal of Physiology & Pharmacology』제8권 제1호, 17~20쪽, 전체 4쪽
- 주제분류
- 의약학 > 의학일반
- 파일형태
- 발행일자
- 2004.01.01
4,000원
구매일시로부터 72시간 이내에 다운로드 가능합니다.
이 학술논문 정보는 (주)교보문고와 각 발행기관 사이에 저작물 이용 계약이 체결된 것으로, 교보문고를 통해 제공되고 있습니다.
국문 초록
영문 초록
PTEN (phosphatase and tensin homolog) is a dual specific phosphatase antagonizing phosphoinositide 3-kinase activity, and has first been cloned as a tumor suppressor for glioma. Although the role of PTEN as a tumor suppressor has been well studied, little is known about signaling mechanisms regulating expression and/or activity of PTEN in the central nervous system. In this study, we investigated whether PTEN expression is regulated by sensory deprivation. P5 rat pups were unilaterally naris-closed, and olfactory bulbs were immunohistochemically analyzed with PTEN antibody at the 7th day after naris closure. PTEN immunoreactivity was found to be down-regulated in both glomerular, external plexiform and subependymal cell layers, suggesting that odor deprivation signals down-regulate expression of PTEN in the olfactory bulb. To the best of our knowledge, this is the first report to suggest that PTEN expression is regulated by sensory deprivation signals in neonatal rats.
목차
해당간행물 수록 논문
- Role of STAT3-Interacting Protein (STIP1) in Δ12-Prostaglandin J2-Induced Cell Death
- Role of Stretch-Activated Channels in Stretch-Induced Changes of Electrical Activity
- Postischemic Treatment with Aminoguanidine Inhibits Peroxynitrite Production in the Rat Hippocampus Following Transient Forebrain Ischemia
- Anti-Apoptotic Effect of Rheum undulatum Water Extract in Pancreatic β-cell Line,
- Economical Sweating Function in Africans: Quantitative Sudomotor Axon Reflex Test
- Nitric Oxide (NO) Inhibites the Neuronal Activities in the Rat Nucleus Tractus Solitarius
- Pharmacokinetics of Dehydroevodiamine Following Intravenous Administration in Rats
- Effect of Amrinone, a Selective Inhibitor of Phosphodiesterase III, on PMNs-induced
- Efffects of Fluoxetine on ATP-induced Calcium Signaling in PC12 Cells
- Decreased Expression of PTEN in Olfactory Bulb of Rat Pub after Naris Closure
참고문헌
관련논문
의약학 > 의학일반분야 BEST
- 교육전담간호사가 주도하는 임상현장교육 프로그램이 신규 간호사의 간호업무성과와 교육 만족도에 미치는 효과
- 간호대학생의 MBTI 성격유형별 의사소통능력, 자아존중감, 학업성취도의 관계
- 일반인을 위한 해부학 만화
의약학 > 의학일반분야 NEW
- Glucocorticoids improve sperm performance in physiological and pathological conditions: their role in sperm fight/flight response
- A comprehensive review of the mental spine
- The anatomical variations of median nerve in Shiraz, Iran
최근 이용한 논문
교보eBook 첫 방문을 환영 합니다!
신규가입 혜택 지급이 완료 되었습니다.
바로 사용 가능한 교보e캐시 1,000원 (유효기간 7일)
지금 바로 교보eBook의 다양한 콘텐츠를 이용해 보세요!