척수전근내 구심흥분을 받는 척수신경세포의 생리학적 특성

• 영문명: Electrophysiological Characteristics of Spinal Neurons Receiving Ventral Root Afferent Inputs in the Cat
• 발행기관: 대한생리학회
• 저자명: 김전(Kim, Jun) 이석호(Lee, Suk-Ho) 정순동(Chung, Soon-Tong)
• 간행물 정보: 『대한생리학회지』제24권 제2호, 389~402쪽, 전체 14쪽
• 주제분류: 의약학 > 의학일반
• 파일형태: PDF
• 발행일자: 1990.12.31

영문 초록

The physiological characteristics of the neurons receiving the ventral root afferent inputs were investigated in the cat. A total of 70 cells were identified in the lumbosacral spinal cord. All these cells responded only to the C-strength stimulation of the distal stump of cut ventral root and the estimated conduction velocities of the VRA fibers were not faster than 4 m/sec. The majority of them were silent in resting state. For 49 cells, their peripheral receptive fields were characterized. Among them, 25 cells were exclusively excited by VRA inputs, 8 were inhibited and the remaining cells recevied both excitatory and inhibitory VRA inputs. According to the response pattern to the mechanical stimuli applied to their receptive fields, only a fourth of them were typical high threshold cell, a sixth, wide dynamic range cells, while remainings were a rather complex cells. Most of the cells receiving VRA inputs, received only the A δ-peripheral nerve inputs. Intravenous injection of morphine decreased the response of spinal cells to the VRA activation. The responses were abolished completely by counter irritation to the common peroneal nerve with C-strength-low frequency stimuli. These physiological properties of the spinal neurons receiving the VRA inputs are differ in some aspect from the spinal neurons receiving nociceptive inputs from the periphery, but still were consistent with the contention that VRA system might carry nociceptive informations arising from the spinal cord and/or neraby surrounding tissues.

키워드

Ventral root afferent Spinal neurons Receptive fields Peripheral nerve inputs Morphine Counter irritation Pain