내측 편도핵의 위산분비 촉진작용에서 미주신경의 역할

• 영문명: Effect of Vagotomy on Gastric Acid Secretory Response to Medial Amygdolid Stimulation
• 발행기관: 대한생리학회
• 저자명: 김명석(Kim, Myung-Suk) 조양혁(Jo, Yang-Hyeok) 윤신희(Yoon, Shin-Hee) 한상준(Hahn, Sang-June) 이덕주(Rhie, Duck-Joo)
• 간행물 정보: 『대한생리학회지』제23권 제2호, 393~400쪽, 전체 8쪽
• 주제분류: 의약학 > 의학일반
• 파일형태: PDF
• 발행일자: 1989.12.31

영문 초록

Sixty-seven conscious rats prepared with chronic gastric fistula were studied to examine the effect of vagotomy on gastric secretory responses to medial amygdaloid stimulation. Gastric acid output was significantly increased by electrical stimulation of the medial amygdaloid nucleus, and the increases in acid secretion were completely eliminated by vagotomy. However, in rats subjected to stimulation of the medial amygdaloid nucleus plus vagotomy, acid output was almost same as that in only vagotomized rats. And vagotomy itself decreased the acid secretion significantly. These results indicate that the influence of electrical stimulaton of the medial amygdaloid nucleus on acid secretion is carried largely via vagus nerves. And also, without electrical stimulation of medial amygdaloid nucleus, acid secretion is controlled by way of vagus in rats. Plasma gastrin concentrations were measured following stimulation of the medial amygdaloid nucleus. Plasma levels of gastrin were not significantly altered by stimulation of the medial amygdaloid nucleus with or without vagotomy. It is therefore inferred from the above results that the facilitatory influence of the medial amygdaloid nucleus on the gastric acid secretion is mediated chiefly via vagal activity and that gastrin is not responsible for the increase in acid secretion in this process.

키워드

Medial amygdaloid nucleus Gastric acid secretion Gastrin Vagus nerve Conscious rat