Reconsidering Clinical Staging Model: A Case of Genetic High Risk for Schizophrenia

• 발행기관: 대한신경정신의학회
• 저자명: TaeYoung Lee Minah Kim SungNyun Kim JunSoo Kwon
• 간행물 정보: 『Psychiatry Investigation』제14권 제1호, 107~109쪽, 전체 3쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2017.01.31

영문 초록

The clinical staging model is considered a useful and practical method not only in dealing with the early stage of psychosis overcoming the debate about diagnostic boundaries but also in emerging mood disorder. However, its one limitation is that it cannot discriminate the heterogeneity of individuals at clinical high risk for psychosis, but lumps them all together. Even a healthy offspring of schizophrenia can eventually show clinical symptoms and progress to schizophrenia under the influence of genetic vulnerability and environmental stress even after the peak age of onset of schizophrenia. Therefore, individuals with genetic liability of schizophrenia may require a more intensive intervention than recommended by the staging model based on current clinical status.

목차

INTRODUCTION

CASE

DISCUSSION

ACKNOWLEDGEMENTS

REFERENCES

키워드

Clinical staging model Schizophrenia Clinical high risk Genetic vulnerability