Design and Methodology of the Korean Early Psychosis Cohort Study

• 발행기관: 대한신경정신의학회
• 저자명: SungWan Kim BongJu Lee JungJin Kim JeChun Yu KyuYoung Lee SeungHee Won SeungHwan Lee SeungHyun Kim S
• 간행물 정보: 『Psychiatry Investigation』제14권 제1호, 93~99쪽, 전체 7쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2017.01.31

영문 초록

The present study details the rationale and methodology of the Korean Early Psychosis Cohort Study (KEPS), which is a clinical cohort investigation of first episode psychosis patients from a Korean population. The KEPS is a prospective naturalistic observational cohort study that follows the participants for at least 2 years. This study includes patients between 18 and 45 years of age who fulfill the criteria for one of schizophrenia spectrum and other psychotic disorders according to the diagnostic criteria of DSM-5. Early psychosis is defined as first episode patients who received antipsychotic treatment for fewer than 4 consecutive weeks after the onset of illness or stabilized patients in the early stages of the disorder whose duration of illness was less than 2 years from the initiation of antipsychotic treatment. The primary outcome measures are treatment response, remission, recovery, and relapse. Additionally, several laboratory tests are conducted and a variety of objective and subjective psychiatric measures assessing early life trauma, lifestyle pattern, and social and cognitive functioning are administered. This long-term prospective cohort study may contribute to the development of early intervention strategies and the improvement of long-term outcomes in patients with schizophrenia.

목차

INTRODUCTION

METHODS

ACKNOWLEDGEMENTS

REFERENCES

키워드

Schizophrenia and psychotic disorder Cohort Early intervention First episode psychosis KEPS