일 대학병원에서 양극성장애 환자의 흡연 특성：정신분열병 환자와의 비교 연구

• 영문명: Smoking Characteristics in Bipolar Disorder： A Comparison Study with Schizophrenia
• 발행기관: 대한신경정신의학회
• 저자명: 이강수 천덕희 김지혜 김현진 조현상
• 간행물 정보: 『신경정신의학』제45권 제4호, 330~336쪽, 전체 7쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2006.07.30

영문 초록

Objectives：This study aimed to investigate smoking characteristics and nicotine dependence severity in bipolar disorder comparing those of schizophrenia. Methods：70 bipolar and 123 schizophrenic patients, diagnosed using DSM-IV-TR criteria and treated at the Severance Mental Health Hospital, were interviewed regarding socio-demographic variables, smoking characteristics and Fagerstrom Test for Nicotine Dependence (FTND), designed to evaluate the intensity of smoking. Results：The rate of current smoking was 60.0% in the bipolar group, and 50.4% in the schizophrenia group. No significant difference was seen in terms of the rate of current smoking between the groups. Rates of having ever smoked also did not differ between bipolar (73%) and schizophrenic patients (65%). Daily cigarette consumption of bipolar patients (15.9 cigarettes/day) was significantly lower than that of schizophrenic patients (21.2 cigarettes/day), but FTND score didn’t appear to differ between bipolar and schizophrenic patients. Bipolar females showed higher rate of current smoking (44%) than schizophrenic females (17%). Among bipolar patients, antipsychotics dose was not correlated with daily cigarette consumption and FTND total score. Age of disease onset didn’t appear to differ between smokers and non-smokers in bipolar group. Conclusion：Although daily consumption was significantly lower in the bipolar group, the rate of smoking and smoking severity in bipolar disorder were as high as in schizophrenia. This fact suggests that the bipolar disorder might be related to the nicotinic acetylcholine system dysfunction as like schizophrenia

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키워드

Bipolar disorder Smoking Schizophrenia