입원 치료 중인 조현병 환자의 비만도와 정신병리

• 영문명: Obesity and Psychopathology of Inpatients with Schizophrenia
• 발행기관: 대한신경정신의학회
• 저자명: 송명선 함 웅 박성용 홍계현 백인호
• 간행물 정보: 『신경정신의학』제54권 제2호, 172~180쪽, 전체 9쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2015.05.31

영문 초록

ObjectivesZZThe aims of this study were to examine the relationship between obesity and psychopathology of inpatients with schizophrenia. MethodsZZEighty four inpatients with schizophrenia and 81 control subjects were recruited. Height and weight were measured for calculation of body mass index (BMI). Symptom severity scales [Positive and Negative Syndrome Scale (PANSS), Brief Psychiatric Rating Scale] and Global Assessment of Functioning Scale (GAF) were conducted in all patients. Comorbid medical conditions, years of education, smoking status, age of onset, duration of illness, and medication history were collected. ResultsZZPatients with schizophrenia had significantly higher BMI and ratio of obesity than control subjects. Among patients, obese patients scored lower on symptom severity scales and better on functional assessment than not obese patients. Multiple regression analysis revealed an association of late onset and being obese with lower PANSS total score and better GAF score in patients. Late onset and being female were inversely related with negative symptom score. The type and dose of antipsychotics showed no association with obesity. ConclusionZZThe results of this study indicate that patients with schizophrenia are likely to be more obese. Some characteristics of patients with less severe psychopathology, such as late onset, being obese, were coincident with the result of previous studies. In addition, the result showing that the heavier the weight of patients, the lower severity of symptoms was repeatedly reported in previous studies. The type and dose of antipsychotics were not associated with obesity. These results prompt further investigation of the relationship among schizophrenia, antipsychotics, and weight gain.

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키워드

Schizophrenia Obesity Psychopathology Severity