Factors Related to Medication Adherence in Outpatients with Schizophrenia under More Than 5 Years of Treatment

• 발행기관: 대한신경정신의학회
• 저자명: Hong Kyu Ihm Sang Hoon Kim Jung Ho Kim Kang Su Ha Hyun Park
• 간행물 정보: 『신경정신의학』제55권 제4호, 397~406쪽, 전체 10쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2016.11.30

영문 초록

Objectives This study aimed to investigate the medication adherence rate and related factors in chronic schizophrenia. Methods A total of 65 (34 male and 31 female) outpatients with schizophrenia and with less than 5 years schizophrenia treatment were randomly selected to participate in the study survey. Medication adherence rate was evaluated by counting remaining tablets. The Korean version of Drug Attitude Inventory-10 (KDAI-10) was used to determine the subjective adherence rate. Adherence was defined as a patient taking more than 80% of their total prescribed medication. Positive KDAI-10 scores indicate good adherence. Results The rate of good adherence was 87.7%. Our analysis showed that an older age (r=0.323, p=0.009), longer duration of illness (r=0.296, p=0.017), employment (F=4.41, p=0.016), remaining married (F=5.26, p=0.008), and being supported by family members, especially spouse or siblings (F=3.02, p=0.025) were significantly associated with good adherence. Presence of symptoms such as delusion (p=0.033) and hallucination (p=0.032) were related to poor adherence. Conclusion The results indicate that future study should investigate patient characteristics associated with medication adherence and analyze the clinician/patient alliance and its affect on adherence. The results also show that further studies might be useful in developing and validating measures of adherence, as well as in designing and evaluating interventions to improve adherent behaviors

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키워드

Chronic schizophrenia Medication adherence Related factors