미세먼지와 인지기능

• 영문명: Particulate Matter and Cognitive Function
• 발행기관: 대한신경정신의학회
• 저자명: 노지현 정한용 이강준
• 간행물 정보: 『신경정신의학』제57권 제1호, 81~85쪽, 전체 5쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2018.02.28

영문 초록

The term “particulate Matter (PM)” refers to the mixture of small-sized solid particles and liquid droplets floating in the air, and is referred to as PM10 (<10 µm), PM2.5 (<2.5 µm) and PM1.0. Much PM is an anthropogenic substance generated by transportation or industrial activities, which is transformed into a second toxic substance by chemical reactions in the atmosphere. PM reaches the brain directly through olfactory transport, or through the blood-brain barrier during systemic circulation. PM that enters the local cerebral circulation causes neuroinflammation through microglial cells and endotoxins. According to previous studies, greater PM exposure results in lower brain volume, especially white matter. Among neurodevelopmental disorders, the correlation between the occurrence of autism spectrum disorder and exposure to PM is widely known. Other studies have found that exposure to PM was associated with low cognitive function and increased rate of cognitive aging. PM can also cause pathology of early Alzheimer s disease and increases the risk of Alzheimer s dementia and mild cognitive impairment.

목차

서론

미세먼지와 신경염증(Neuroinflammation)

미세먼지와 뇌 용적

미세먼지와 신경발달질환

미세먼지와 인지기능 저하

미세먼지와 알츠하이머병 치매

결론

Notes

Acknowledgments

References

키워드

미세먼지 대기오염 알츠하이머병 치매