Lorazepam이 가토 혈중 주정농도에 미치는 영향에 관한 실험적 연구

• 영문명: EFFECTS OF LORAZEPAM ON BLOOD ALCOHOL LEVEL IN RABBITS
• 발행기관: 대한신경정신의학회
• 저자명: 尹景秀
• 간행물 정보: 『신경정신의학』제16권 제4호, 340~348쪽, 전체 9쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 1977.11.30

영문 초록

Lorazepam is a new benzodiazepine derivative with potent anxiolytic and sedative properties inherent in the group. Many studies suggest that it is a more potent drug with minimal side effects. There is a structural similarity between lorazepam and oxazepam, since both result from a demethylation and hydroxylation of diazepam, with lorazepam being distinguished by the presence of a chlorophenyl side chain. It has been reported that chlorpromazine, lithium and several psychotropic drugs elevated the blood alcohol level in rabbits. In view of these findings, the author conducted an animal experiment to investigate the effect of lorazepam on blood alcohol level in rabbits.

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