편집성 정신분열증과 비편집성 정신분열증 환자의 Chlorpromazine 근육주사에 따른 혈청 Prolactin 값

• 영문명: Serum Prolactin before and after Chlorpromazine Injection in Paranoid and Nonparanoid Schizophrenic Disorders
• 발행기관: 대한신경정신의학회
• 저자명: 백인호 고효진
• 간행물 정보: 『신경정신의학』제22권 제1호, 10~14쪽, 전체 5쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 1983.02.28

영문 초록

For comparison of paranoid and nonparanoid types of schizophrenia, the authors measured serum prolactin value in both groups of schizophrenics before and after the intramuscular injection of chlorpromazine (25mg) by the radioim munoassay technique. The subjects were 16 paranoid and 7 nonparanoid schizophrenics whose diagnoses were made on the criteria of the Diagnostic and Stastistical Manual of Mental Disorders (D SM - III). The results were as follows： 1. Mean . serum prolactin value of the entire subjects was within normal range before the intram usbular injection of chlorpromazine. And there was no significant difference between paranoid and nonparanoid groups. 2. Follow nig the injection of 25mg chlorpromazine, serum prolactin values were found to be significantly increased in b oth groups. However, no significant difference was also found between the two groups. This study suggested that it would be difficult to distinguish paranoid type of schizophrenic disorder by measuring serum prolactin values.

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