만성정신분열장애 환자의 시각유발전위 : 대뇌기능의 비대칭성에 대한 예비적 연구

• 영문명: Visual Evoked Potential in Chronic Schizophrenics: A Preliminary Study on Cerebral Asymmetry
• 발행기관: 대한신경정신의학회
• 저자명: 박원명 김용찬 백인호
• 간행물 정보: 『신경정신의학』제25권 제3호, 357~363쪽, 전체 7쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 1986.08.31

영문 초록

The etiology and pathophysiology of schizo- phrenics has not been precisely described until now. There has been many studies which have elucidated the neuroanatomical and neurophysiological abnormalities of schizophrenics using the up to date biological measurement methods like brain CT, positron emission tomography, cerebral evoked potentials, and measuring regional cerebral blood flows. The authors have chosen the visual evoked potential which have recently turned out to be one of important neurophysiological diagnostic tools, and tried to confirm the asymmetry of cerebral function & local dysfunction in schizophrenics. We have performed visual evoked potential to 20 patients admitted to Kangnam St. Mary’s Hospital of Catholic Medical College from Oct. 1985 till March 1986, and to 20 normal controls, and the results were as follows; 1) Amplitude at stimulus intensity of 0.6 Joule (Median, Range); Patient group showed 5.6/^V, 9 .9 ^ V at 01 site, 5.9찌 10.3/^V at O2 site and control group showed 6.4찌 13.4^ V at Oi site, 6.3^ V, 10.6/^V at 0 2 site. 2) Amplitude at stimulus intensity of 1.2 Joule (Median, Range); Patient group showed 5.2 18.4 ᄍV at Oi site, 7.0^V, 1 7 . 2 at O2 site and control group showed 7.7MW , 18.2/^V at Oi site, 5.8AV, 16.5 at O2 site. 3) Latency at stimulus intensity of 0.6 Joule (Mean 土 SD) ; Patient group showed 108.0 土 13.7 msec at Oi site, 108.0 土 13.6 msec at O2 site and control group showed 107.2 土 11.1 msec at Oi site, 109.3 ±10.6 msec at O2 site. 4) Latency at stimulus intensity of 1.2 Joule (Mean 土 SD); Patient group showed 111.6 土 4.6 msec at Oi site, 109.8 ±17.2 msec at O2 site and control group showed 103.7 土 11.0 msec at Oi site, 103.5 土 11.8 msec at O2 site. 5) There was no asymmetry of visual evoked potential obtained from right & left hemisphere of both patients & controls. 6) We have also compaired the amplitude & latency and found no significant difference statistically between the two groups

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