학술논문
家族性 정신분열병과 非家族性 정신분열병과의 硏究
이용수 2
- 영문명
- Comparative Study of Schizophrenic Patients with and without Family History
- 발행기관
- 대한신경정신의학회
- 저자명
- 金圭泰 禹鍾仁
- 간행물 정보
- 『신경정신의학』제26권 제1호, 62~74쪽, 전체 13쪽
- 주제분류
- 의약학 > 정신과학
- 파일형태
- 발행일자
- 1987.02.28
4,360원
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국문 초록
영문 초록
Since K raerelin described dementia preaecox,
Schizophrenia has been w idely considered to be a
heterogenous syndrom e. Various approaches have
been taken in attem pting to subdivide this disorder
into m ore homogenous groups.
In addition, it also has been considered that
genetic factor may contribute to schizophrenia
predisposition and schizophrenia may be genetically
heterogenous. The existence of a characteristic
that expresses a genetic predisposition to schizophrenia
wouJd be helpful in defining a genetically
m ore homogenous group.
So, th is study was perform ed to evaluate
assumptions that schizophrenia could be differentiated
on the basis o f fam ily history. We compared
tw o groups o f patients distinguished by the presence
o r absence of fam ily history, each groups
included 34 schizophrenic patients matched by age
and sex. these tw o groups o f patients were
evaluated on the aspect o f psychopathology,
neruom otor function abnorm ality and pathologic
reflex.
The results are as follow s :
1) There was no significant difference in age o f
onset, duration o f illness, frequency o f hospitalization
and dosage o f drug detween tw o groups.
2) A t the tim e o f adm ission there was no
significant difference in the psychopathology between
tw o groups.
3) As fo r the present psychopathology, m ost
patients had rem itted from active psychotic symptoms,
patiens w ith fam ily h isto ry had significantly
more negative symptoms than those w ithout family
h isto ry, and patients w ith fam ily h isto ry
showed singificantly more increasem ent in negative
symptoms from the tim e o f admission to the
present than those w ithout fam ily history.
4) We divided the schizophrenia in to three subtypes
: postive, negative and m ixed schizophrenia.
A t the tim e o f admission there was no significant
difference in the rate o f these three subtypes
between tw o groups but at present, the proportion
o f negative schizophrenic patients were increased
in the group o f patients w ith fam ily
history and that o f m ixed schizophrenic patients
were increased in the guoup o f patients w ithout
fam ily history.
5) The to ta l score o f neurom otor function te st
w ere n o t significantly d iffe re n t betw een tw o
groups. In the individual te st the group o f patients
w ith fam ily history showed significantly
more abnormal patients in the heel to tap test,
and significantly slower speed in the successive
finger opposition and heel to tap te s t
6) There was no significant difference in the
pathologic re fle x between tw o groups.
7) Among patients w ithout fam ily history, there
was sig n itica n t co rre la tio n betw een negative
symptoms and neurom otor function abnorm ality.
목차
서 론
연구대상 및 방법
결 과
고 찰
결 론
REFERENCES
키워드
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