학술논문
정신분열병의 양성증상 및 음성증상
이용수 43
- 영문명
- Positive Symptoms and Negative Symptoms of Schizophrenia
- 발행기관
- 대한신경정신의학회
- 저자명
- 유재학 양병환
- 간행물 정보
- 『신경정신의학』제27권 제3호, 548~571쪽, 전체 24쪽
- 주제분류
- 의약학 > 정신과학
- 파일형태
- 발행일자
- 1988.05.31
5,680원
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국문 초록
영문 초록
The concept of positive and negative symptoms of schizophrenia introduced by Jackson in
1931, had been ignored by psychiatric professionals. Since Crow and Andreasen tried to prove
clinical significance of the concept, it has drawn much clinical attention. Many previous authors
attempted to prove this dichotomous concept by cross-sectional study which mostly resulted
in affirmative conclusion. However, there is no longitudinal study with follow-up evaluation
of the positive and negative symptoms of schizophrenia.
The authors attempted to evaluate the validity of the dichotomous concept by cross-sectional
study and the stability of the two dimensions by longitudinal study for 12 weeks.
Subject of the study was 98 schizophrenics who had been admitted to the Seoul National Mental
Hospital from March to July 1987. The subjects were divided into the three groups according
to Andreasen’ s classification ; the postitive symptom group(n=35), the negative symptom
group(n=18) and the mixed symptom group(n=45). The DSM-III-R was used for diagnostic
criterion. Scale for the Assessment of the Positive Symptoms, Scale for the Assessment of the
Negative Symptoms, Brief Psychiatric Rating Scale and Mini Mental State Examination were
used for symptom evaluation.
The results were as follows ;
1) Sociodemographic characteristics, present illness, previous treatment history and hereditary
loading showed no significant difference among the three groups. Only premorbid social adjustment
was poorer in the mixed symptom group.
2) The patterns of symptom change showed significant difference among the three groups.
3) During the 12 week follow-up, 33 % of the positive symptom group and 34 % of the negative
symptom group were retained in their original group.
4) Sixty eight percent of all cases shifted in their symptom to the other groups. Fifty four
percent of all cases shifted in their symptom according to Crow’ s hypothetical process of “positive
mixed negative another mixed”, and only 15% shifted against the above process.
5) Symptom severity of the positive symptom decreased during the follow-up, whereas that
of the negative symptom manifested unchanged. Frequency of positive symptom as a whole
decreased and resulted in the increase of negative symptom.
6) Decrease of positive symptom was highly correlated to the decrease of dosage of antipsychotics.
Consequently, it was suggested that dichotomous concept of schizophrenia, the positive symptom
group and the negative symptom group, is course-related phenomenon rather thanoriginally
separated entity.
목차
서 론
대상 및 방법
결 과
고 찰
결 론
REFERENCES
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