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• 영문명: Brainstem Auditory Evoked Potentials in Chronic Alcoholics
• 발행기관: 대한신경정신의학회
• 저자명: 박영숙 김정기 김종길
• 간행물 정보: 『신경정신의학』제27권 제6호, 995~1002쪽, 전체 8쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 1988.11.30

영문 초록

Brainstem auditory evoked potentials (BAEP) were studied in 11 male chronic alcoholics and 11 normal male controls. Alcoholic patients met the Research Diagnostic Criteria and the criteria of the DSM-III for alcoholism, with a mean age of 46 years and drinking history for an average of 22 years. Control subjects were age matched males recruited from hospital employees free of medical problems. The results were as follows: 1) The statistical analyses using two tailed t-test indicate that mean latency of peak V (P < 0. 01) and interpeak latencies of III-V (P〈0.05) & I- V (P〈0.05) were significantly prolonged in the alcoholic group compared to the control group. 2) Seven of the eleven patients(64%) displayed significant increases of the interpeak latencies of BAEP. 3) Five of the above seven patients displayed a significant increase of the I- V interval of BAEP. These results provide an evidence for the involvement of the brainstem as well as the neocortex in chronic alcoholism, suggesting that brainstem abnormalities in chronic alcoholics are common. Therefore we suggest BAEP could be well used as an noninvasive and objective measure of brainstem lesion in cases of chronic alcoholism and also a guide method for prognostic information as the previously reported in the literature of other countries.

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