학술논문
Choroidal Thickening Induced by Pioglitazone in Diabetic Patients
이용수 0
- 영문명
- 발행기관
- 대한안과학회
- 저자명
- Ju Seouk Lee Chang Zoo Kim Seung Uk Lee Sang Joon Lee
- 간행물 정보
- 『The Korean Journal of Ophthalmology』Vol.38 No.5, 331~341쪽, 전체 11쪽
- 주제분류
- 의약학 > 의학일반
- 파일형태
- 발행일자
- 2024.10.31
4,120원
구매일시로부터 72시간 이내에 다운로드 가능합니다.
이 학술논문 정보는 (주)교보문고와 각 발행기관 사이에 저작물 이용 계약이 체결된 것으로, 교보문고를 통해 제공되고 있습니다.
국문 초록
Purpose: This study aimed to determine the changes in choroidal thickness induced by pioglitazone in diabetic patients.
Methods: A total of 261 patients diagnosed with type 2 diabetes who had taken oral pioglitazone for more than 6 months were included in the study. After excluding patients who did not undergo regular eye examinations or who had ophthalmic surgery/interventions during the treatment period, a total of 40 eyes were included. The study examined the duration and dosage of pioglitazone, patient age, ocular axial length, refraction, glycated hemoglobin, systolic blood pressure, corrected visual acuity, macular thickness, choroidal thickness, and choroidal vascular index. Patients were categorized into a high-dose group if their pioglitazone dose was 30 mg or more per day, and a low-dose group if it was 15 mg or less. Choroidal thickness was measured below the subfovea and a 500 μm radius nasal and temporal to that location.
Results: Choroidal thickness significantly increased after 6 and 12 months of pioglitazone (6.70 and 13.65 μm, respectively) in all subjects. When stratified by pioglitazone dosage, choroidal thickness increased at 6 and 12 months in both high-dose group (4.48 and 0.84 μm, respectively) and low-dose groups (6.85 and 21.45 μm, respectively), with a greater change observed in the low-dose group (p < 0.05). Based on the location of choroidal thickness measurements, a significant increase in choroidal thickness was observed at 6 and 12 months of pioglitazone treatment in the subfoveal (7.00 and 13.15 μm, respectively) and nasal regions (6.43 and 19.24 μm, respectively), while a significant increase was only observed after 6 months of treatment in the temporal region (8.53 μm, p < 0.05). The largest increase in choroidal thickness was observed in the nasal side.
Conclusions: This study found that choroidal thickness increased in diabetic patients after taking pioglitazone. Regular eye examinations are recommended for diabetic patients who are on pioglitazone.
영문 초록
목차
Materials and Methods
Results
Discussion
References
키워드
해당간행물 수록 논문
- Clinical Features and Visual Outcome of Infectious Keratitis Associated with Orthokeratology Lens in Korean Pediatric Patients
- Blastic Plasmacytoid Dendritic Cell Neoplasm with Periorbital Ecchymosis and Massive Subconjunctival Hemorrhage as a Presenting Sign: A Case Report
- Scleral Rupture during Scleral Buckle and Cryotherapy for Rhegmatogenous Retinal Detachment: A Case Report
- Retinal Toxicity Due to Presumed Long-Standing Migratory Perfluorocarbon Liquids: A Case Report
- “Pig Snout” Canaliculus: A Rare Case of Actinomyces Canaliculitis in Double Puncta
- Choroidal Thickening Induced by Pioglitazone in Diabetic Patients
- Changes in Iridotrabecular Contact and Intraocular Pressure after Phacoemulsification in Primary Angle-Closure Disease Spectrum
- Health-related Quality of Life in Children with Vernal Keratoconjunctivitis in Malaysia
- Long-term Outcomes of Bilateral Lateral Rectus Recession Using a Modified Normogram for Targeting Small Overcorrection in Intermittent Exotropia
- Incidence and Characteristics of Intraocular Lens Dislocation in South Korea from 2002 to 2021: A Nationwide Population-based Study
- Higher Order Aberrations in Patients with Unilateral Nasolacrimal Duct Obstruction
- Two-year Outcomes of Intravitreal Aflibercept Injection for Neovascular Age-related Macular Degeneration with “Observe before Treat-and-Extend” Method
- Ultra-Widefield Fluorescein Angiographic Features Influencing Visual Prognosis in Coats Disease
- Coats-like Exudative Retinopathy in a Patient with Joubert Syndrome with CEP290 Mutation: A Case Report
참고문헌
관련논문
의약학 > 의학일반분야 BEST
- 간호대학생의 인공지능 활용 간호수행 자신감에 영향을 미치는 요인
- 국내 의료기관의 환자안전사고 관련 요인 분석: 2019-2022년 환자안전보고 데이터 활용 이차분석 연구
- 지역사회 인지저하 전·후기 노인의 건강 및 돌봄 요구 실태
의약학 > 의학일반분야 NEW
- 한국 응급실 간호사의 임종간호 태도에 미치는 영향요인: 횡단적 조사 연구
- Development and validation of machine learning models to predict prediabetes using dietary intake data in young adults in Korea: a cross-sectional study
- Effects of environmental enrichment and caloric restriction on hippocampal changes in early adult rats
최근 이용한 논문
교보eBook 첫 방문을 환영 합니다!
신규가입 혜택 지급이 완료 되었습니다.
바로 사용 가능한 교보e캐시 1,000원 (유효기간 7일)
지금 바로 교보eBook의 다양한 콘텐츠를 이용해 보세요!