저용량 I-131 투여시 Apron 착용여부에 따른 차폐효과에 대한 고찰

• 영문명: Consideration on Shielding Effect Based on Apron Wearing During Low-dose I-131 Administration
• 발행기관: 대한핵의학기술학회
• 저자명: 김일수(Ilsu Kim) 김호신(Hosin Kim) 류형기(Hyeonggi Ryu) 강영직(Yeongjik Kang) 박수영(Suyoung Park) 김승찬(Seungchan Kim) 이귀원(Guiwon Lee)
• 간행물 정보: 『핵의학기술』Vol.20 No.1, 32~36쪽, 전체 5쪽
• 주제분류: 의약학 > 방사선과학
• 파일형태: PDF
• 발행일자: 2016.05.30

영문 초록

Purpose In nuclear medicine examination, ¹³¹I is widely used in nuclear medicine examination such as diagnosis, treatment, and others of thyroid cancer and other diseases. ¹³¹I conducts examination and treatment through emission of Ɣ ray and ß- ray. Since ¹³¹I (364 keV) contains more energy compared to ⁹⁹ᵐTc (140 keV) although it displays high integrated rate and enables quick discharge through kidney, the objective of this study lies in comparing the difference in exposure dose of ¹³¹I before and after wearing apron when handling ¹³¹I with focus on 3 elements of external exposure protection that are distance, time, and shield in order to reduce the exposure to technicians in comparison with ⁹⁹ᵐTc during the handling and administration process. When wearing apron (in general, Pb 0.5 mm), ⁹⁹ᵐTc presents shield of over 90% but shielding effect of ¹³¹I is relatively low as it is of high energy and there may be even more exposure due to influence of scattered ray (secondary) and bremsstrahlung in case of high dose. However, there is no special report or guideline for low dose (74 M㏃) high energy thus quantitative analysis on exposure dose of technicians will be conducted based on apron wearing during the handling of ¹³¹I. Materials and Methods With patients who visited Department of Nuclear Medicine of our hospital for low dose ¹³¹I administration for thyroid cancer and diagnosis for 7 months from Jun 2014 to Dec 2014 as its subject, total 6 pieces of TLD was attached to interior and exterior of apron placed on thyroid, chest, and testicle from preparation to administration. Then, radiation exposure dose from ¹³¹I examination to administration was measured. Total procedure time was set as within 5 min per person including 3 min of explanation, 1 min of distribution, and 1 min of administration. In regards to TLD location selection, chest at which exposure dose is generally measured and thyroid and testicle with high sensitivity were selected. For preparation, 74 MBq of ¹³¹I shall be distributed with the use of 2 ㎖ syringe and then it shall be distributed after making it into dose of 2 ㎖ though dilution with normal saline. When distributing ¹³¹I and administering it to the patient, 100 ㎖ of water shall be put into a cup, distributed ¹³¹I shall be diluted, and then oral administration to patients shall be conducted with the distance of 1m from the patient. The process of withdrawing 2㎖ syringe and cup used for oral administration was conducted while wearing apron and TLD. Apron and TLD were stored at storage room without influence of radiation exposure and the exposure dose was measured with request to Seoul Radiology Services. Results With the result of monthly accumulated exposure dose of TLD worn inside and outside of apron placed on thyroid, chest, and testicle during low dose ¹³¹I examination during the research period divided by number of people, statistics processing was conducted with Wilcoxon Signed Rank Test using SPSS Version. 12.0K. As a result, it was revealed that there was no significant difference since all of thyroid (p = 0.345), chest (p = 0.686), and testicle (p = 0.715) were presented to be p > 0.05. Also, when converting the change in total exposure dose during research period into percentage, it was revealed to be -23.5%, -8.3%, and 19.0% for thyroid, chest, and testicle respectively. Conclusion As a result of conducting Wilcoxon Signed Rank Test, it was revealed that there is no statistically significant difference (p > 0.05). Also, in case of calculating shielding rate with accumulate exposure dose during 7 months, it was revealed that there is irregular change in exposure dose for inside and outside of apron. Although the degree of change seems to be high when it is expressed in percentage, it cannot be considered a big change since the unit of accumulated exposure dose is in decimal points. Therefore, regardless of wearing apron

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키워드

¹³¹I TLD Apron Wilcoxon Signed Rank Test