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학술논문

Radiotherapy trend in elderly hepatocellular carcinoma: retrospective analysis of patients diagnosed between 2005 and 2017

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영문명
Radiotherapy trend in elderly hepatocellular carcinoma: retrospective analysis of patients diagnosed between 2005 and 2017
발행기관
대한방사선종양학회
저자명
Bong Kyung Bae Jeong Il Yu Hee Chul Park Myung Ji Goh Yong-Han Paik
간행물 정보
『대한방사선종양학회지』제41권 제2호, 98~107쪽, 전체 10쪽
주제분류
의약학 > 종양학
파일형태
PDF
발행일자
2023.06.30
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Purpose: To report the trends of radiotherapy in the management of elderly patients with hepatocellular carcinoma (HCC). Materials and Methods: We retrospectively reviewed patients who entered HCC registry of Samsung Medical Center between 2005 and 2017. Patients who were 75 years or older at the time of registration were defined as elderly. They were categorized into three groups based on the year of registration. Radiotherapy characteristics were compared between the groups to observe differences by age groups and period of registration. Results: Out of 9,132 HCC registry patients, elderly comprised 6.2% (566 patients) of the registry, and the proportion increased throughout the study period (from 3.1% to 11.4%). Radiotherapy was administered to 107 patients (18.9%) in elderly group. Radiotherapy utilization in the early treatment process (within 1 year after registration) has rapidly increased from 6.1% to 15.3%. All treatments before 2008 were delivered with two-dimensional or three-dimensional conformal radiotherapy, while more than two-thirds of treatments after 2017 were delivered with advanced techniques such as intensity-modulated radiotherapy, stereotactic body radiotherapy, or proton beam therapy. Overall survival (OS) of elderly was significantly worse than younger patients. However, for patients who received radiotherapy during the initial management (within one month after registration), there was no statistically significant difference in OS between age groups. Conclusion: The proportion of elderly HCC is increasing. Radiotherapy utilization and adoption of advanced radiotherapy technique showed a consistently increasing trend for the group of patients, indicating that the role of radiotherapy in the management of elderly HCC is expanding.

목차

Introduction
Materials and Methods
Results
Discussion and Conclusion
Statement of Ethics
Conflict of Interest
Funding
Author Contributions
Data Availability Statement
References

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APA

Bong Kyung Bae,Jeong Il Yu,Hee Chul Park,Myung Ji Goh,Yong-Han Paik. (2023).Radiotherapy trend in elderly hepatocellular carcinoma: retrospective analysis of patients diagnosed between 2005 and 2017. 대한방사선종양학회지, 41 (2), 98-107

MLA

Bong Kyung Bae,Jeong Il Yu,Hee Chul Park,Myung Ji Goh,Yong-Han Paik. "Radiotherapy trend in elderly hepatocellular carcinoma: retrospective analysis of patients diagnosed between 2005 and 2017." 대한방사선종양학회지, 41.2(2023): 98-107

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