A comparison study of the effects of loratadine-pharmacopuncture and loratadine-oral administration based on traditional Korean medicine theory on anaphylactic reaction in mice

• 발행기관: 셀메드 세포교정의약학회
• 저자명: Hyun-Min Kim, Hyun-Min Kim, Min-Jung Lee, Min-Gi Cho, Deok Kang, Yu-Kyung Kim, Changmin Kim 외 95명
• 간행물 정보: 『셀메드』Volume 8 Issue 1, 1~4쪽, 전체 4쪽
• 주제분류: 의약학 > 의학일반
• 파일형태: PDF
• 발행일자: 2018.02.28

영문 초록

Pharmacopuncture, or herbal acupuncture, is a new form of therapy derived from combinations of two traditional therapeutic methods, herbal medicine and acupuncture therapy. To compare the efficacy between loratadine-pharmacopuncture (LP) and loratadine-oral administration (LO), the effect of loratadine was investigated in murine models. Anti-anaphylactic effects of loratadine treatments were investigated in compound 48/80-induced systemic anaphylactic reaction and passive cutaneous anaphylaxis (PCA). LP treatment significantly inhibited the compound 48/80-induced systemic anaphylactic reaction and PCA. The effect between LP and LO were on a similar level. These results indicate that LP can be used as an alternative method for LO in case of emergency.

키워드

loratadine-pharmacopuncture systemic anaphylactic reaction passive cutaneous anaphylaxis