솔잎(Pinus densiflora leaf) 추출물의 항비만효과

• 영문명: Anti-Obesity Effect of Pinus densiflora Leaf Extracts
• 발행기관: 한국자원식물학회
• 저자명: 최민영(Min Yeong Choi) 신별(Byel Shin) 유주형(Ju Hyeong Yu) 여주호(Joo Ho Yeo) 이재원(Jae Won Lee) 금나경(Na Gyeong Geum) 안미연(Mi-Yun An) 정진부(Jin Boo Jeong)
• 간행물 정보: 『한국자원식물학회지』제35권 제2호, 385~389쪽, 전체 5쪽
• 주제분류: 농수해양 > 기타농수해양
• 파일형태: PDF
• 발행일자: 2022.04.30

영문 초록

In this study, we measured the inhibitory activity of Pinus densiflora leaf (PDL) against excessive lipid accumulation in mouse preadipocyte, 3T3-L1 cells to investigate whether PDL exerts anti-obesity activity. Lipid accumulation and the protein level were measured using Oil red O staining assay and Western blot analysis, respectively. We observed that PDL inhibited excessive lipid accumulation and decreased the expression of CEBPα, PPARγ and perilipin-1 related to lipid accumulation in 3T3-L1 cells. Therefore, considering these results, PDL can be used as a potential agent for anti-obesity.

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키워드

Anti-obesity activity Adipocytes Pinus densiflora 3T3-L1 cells