황금찰수수 도정부산물의 항산화 및 항염증 활성

• 영문명: Antioxidative and Anti-inflammatory Activity of Extract from Milling By-products of Sorghum Cultivar, ‘Hwanggeumchal’
• 발행기관: 한국작물학회
• 저자명: 나지은(Ji-Eun Ra) 박지영(Ji-Young Park)서우덕(Woo Duck Seo) 심은영(Eun-Yeong Sim) 고지연(Jee Yeon Ko) 남민희(Min-Hee Nam) 정일민(Ill-Min Chung) 한상익(Sang-Ik Han)
• 간행물 정보: 『한국작물학회지』제59권 제4호, 463~469쪽, 전체 7쪽
• 주제분류: 농수해양 > 기타농수해양
• 파일형태: PDF
• 발행일자: 2014.12.30

영문 초록

Sorghum has been consumed as one of the important staple food in the semiarid tropics of Africa and Asia. Sorghum is rich in starch, protein, essential vitamins and minerals and grows relatively well in dry climate regions when it compared with other staple food crops. Sorghum has taken an increased interest due to several studies that report about the beneficial effects of sorghum on human health. In the present study, we investigated the antioxidative and activity of extract of milling by-products (hull and bran) of Korean sorghum cultivar, ‘Hwanggeaumchal’ as well as its grain. Hull extract showed the highest total polyphenol contents (29.7±0.2 mg GAE/100 g) and major four pigments content (322.6±14.5 mg/100 g). From results of 2,2 -azinobis-(3- ethylbenzothiazoline-6-sulfonate (ABTS) radical scavenging activity, hull extract (IC50, 6.3±0.1 μg/ mL) was also showed the strongest antioxidative effects. Bran and grain showed similar polyphenol, pigments contents and antioxidative effects. We determined cell viability by MTT assay and evaluated the anti-inflammatory activity by measuring nitric oxide (NO) of hull, bran and grain methanol extract (0.5% HCl v/v) on RAW 264.7 cells. Hull extract treatment was significantly decreased NO production with dose-dependant manner. Apigeninidin as one of the major pigment of hull was showed inhibitory activity against NO production without cytotoxicitiy. Therefore, sorghum milling by-products can be used as a good source of antioxidative and anti-inflammatory agents.

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antioxidative activity anti-inflammatory activity sorghum hwanggeumchal milling by-product