노인에서 코로나19 감염 중증도와 관련된 요인

• 영문명: Factors Associated with Severe Outcomes of the Coronavirus Disease 2019 among Elderly Patients in South Korea
• 발행기관: 대한임상노인의학회
• 저자명: Seung Wan Hong Ji yeon Lee Miri Hyun Jae Seok Park Jae Hyuck Lee Young Sung Suh Hyun ah Kim Dae Hyun Kim
• 간행물 정보: 『대한임상노인의학회지』대한임상노인의학회지 제22권 제1호, 34~39쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2021.06.30

영문 초록

Background: The coronavirus disease 2019 (COVID-19) has been rapidly spreading globally since its outbreak in December 2019 at Wuhan, Hubei Province, China. The mortality rate of the older population with COVID-19 is particularly high. Therefore, investigating risk factors related to severe outcomes in older COVID-19 patients is important for effective management of the disease. This study aimed to assess the epidemiological and medical factors in older patients to investigate the risk factors related to the severe outcomes of COVID-19. Methods: We collected clinical and demographic data and assessed the laboratory parameters, radiologic findings, symptoms, and outcomes of older patients with COVID-19. Among the 248 older patients with COVID-19, of whom 99 had severe COVID-19. Results: The mortality rate was 6.5%. Older and male patients have more severe COVID-19 outcomes. White blood cell counts and creatine phosphokinase, C-reactive protein, procalcitonin, aspartate transaminase, lactate dehydrogenase, and creatinine levels were higher in the severe outcome group. Age, sex, chest X-ray findings, neutrophil count, C-reactive protein level, lactate dehydrogenase level, and albumin level, total number of symptoms, within-family exposure history, and in-hospital exposure history were associated with severe outcomes in the logistic regression model. Conclusions: Age, C-reactive protein and lactate dehydrogenase levels, and the total number of symptoms were important risk factors among older patients with COVID-19. Therefore, older patients with these factors require more careful attention and medical care.

목차

INTRODUCTION

MATERIALS AND METHODS

RESULTS

DISCUSSION

CONFLICTS OF INTEREST

REFERENCES

키워드

Coronavirus disease (COVID-19) Older patients Risk factors Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)