천연물 도포가 UV-B파로 손상된 C57BL/6 mouse 피부의 색소침착과 염증생성에 미치는 영향

• 영문명: Effects of natural extracts on UVB-induced pigmentation and inflammation in C57BL/6 mouse skin
• 발행기관: 한국환경보건학회
• 저자명: 최욱희(Wook-Hee Choi) 안형수(Hyoung-Soo Ann) 최태윤(Tae-Youn Choi) 진소영(So-Young Jin) 안령미(Ryoung-Me Ahn)
• 간행물 정보: 『1. 한국환경보건학회지』제32권 제5호, 492~498쪽, 전체 7쪽
• 주제분류: 공학 > 환경공학
• 파일형태: PDF
• 발행일자: 2006.10.30

영문 초록

Ultraviolet(UV) radiation causes a variety of biological effects on the skin, including inflammation, pigmentation, photoaging and cancer. Free radicals are involved in inflammatory skin reactions induced by UVB radiation. In this study, we investigated the effects of antioxidants(Tea, Korean red ginseng, Ginkgo biloba extract) on UVB-induced skin damage. Tea, KRG and EGb 761 were topically treated to dorsal skin of ICR mouse. The mice were also treated soon after 1MED (1.4 KJ/m2) of UVB irradiation. Skin pigmentation of irradiated mouse was observed by a chromameter after 2 weeks. Topical application of Tea, KRG and EGb 761 for 2 weeks decreased skin pigmentation compared to UVB control group(p<.05). Tea, KRG and EGb 761 also reduced UVB-induced infiltration of inflammatory cells. These results showed that Tea, KRG and EGb 761 as a topical application may have preventive effect against UVB-induced skin damage.

목차

Ⅰ. 서론

Ⅱ. 연구방법

Ⅲ. 결과 및 고찰

Ⅳ. 결론

키워드

UVB radiation Korean red ginseng(KRG) Ginkgo biloba extract(EGb 761) tea