유방암의 연수막 파종과 동반된 시신경 침윤 1예

• 영문명: A Case of Presumed Optic Nerve Infiltration Associated with the Leptomeningeal Seeding of the Breast Cancer
• 발행기관: 대한검안학회
• 저자명: 박지웅(Ji Woong Park) 서영승(Young Seung Seo) 경성은(Sung Eun Kyung)
• 간행물 정보: 『Annals of optometry and contact lens』Vol.14 No.1, 50~53쪽, 전체 4쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2015.03.30

영문 초록

Purpose: We report a case of presumed optic nerve infiltration associated with the leptomeningeal seeding of the 37- year-old breast cancer patient complaining sudden diplopia. Case summary: A 37-year-old woman receiving chemotherapy because of inoperable breast cancer presented to us with a sudden onset diplopia. The ophthalmologic examination demonstrated a 25 prism diopter esotropia at primary gaze, 30 prism diopter esotropia at the right gaze and abduction limitation in the right eye. The fundus exam showed bilateral papilledema. Visual acuity, anterior segment exam, visual field test and color vision test were normal. Brain magnetic resonance imaging showed no parenchyme infiltration and no enhancement lesion. In the results of cerebral spinal fluid exam, the elevated intracranial pressure (345 mm Hg) and the malignant cells were observed. The diplopia was improved right after lumbar puncture. But 1-month after controlling the intracranial pressure, the aggravating disc edema and color vision abnormalities of the both eyes were founded. Conclusions: Breast cancer is the most common primary site of the ocular metastatic tumors. In the eye, highly vascularized choroid is the most frequently metastasis site of the breast cancer. We experienced presumed optic nerve infiltration, which the papilledema were aggravated while controlling intracranial pressure, in patient diagnosed as the leptomeningeal seeding of breast cancer.

목차

증례보고

고 찰

REFERENCES

키워드

Abducens nerve palsy Breast cancer Leptomeningeal seeding Optic nerve infiltration Papilledema