학술논문
Human umbilical cord and its vessels: a histomorphometric study in difference severity of hypertensive disorders of pregnancy
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- 영문명
- 발행기관
- 대한해부학회
- 저자명
- Santhi Chillakuru Subhadra Devi Velichety Vijayaraghavan Rajagopalan
- 간행물 정보
- 『Anatomy and Cell Biology』Vol.53(1), 68~75쪽, 전체 8쪽
- 주제분류
- 의약학 > 의학일반
- 파일형태
- 발행일자
- 2020.03.30
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국문 초록
영문 초록
The umbilical cord (UC) is a platform for fetal nourishment and growth. The fetus, mother and placenta with UC form a triad, which contributes to pregnancy outcome. When pregnancy is complicated by a medical condition like hypertension, affects both maternal and fetal health. Being a fetal structure it can be used as a window to know the maternal dysfunctions and their impacts on fetal wellbeing. The present study is to explore the histomorphometric changes of the UC and its vessels involved in the development of hypertension during pregnancy. Sixty UCs were used and the following parameters, total UC area; total vessel area; jelly area; wall area, luminal area and wall thickness of umbilical arteries 1 and 2 and vein were studied using ImageJ software. From the results, the mean differences of above parameters of hypertensive UCs were found to be lesser than control and it was significantly higher in cases of severe preeclampsia (P≤0.05). From the present study, we conclude hypertensive cords and its vessels are associated with significant structural changes. Since it is a global health issue it is important to know the factors contributing it to diagnose and prevent.
목차
Introduction
Materials and Methods
Results
Discussion
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